The research activity is part of the activities coordinated by the TECH4MILK Platform who engages a wide spectrum of the Piemonte dairy production chain in order to enhance its sustainability from primary production to processing, to computerize certification and traceability, to improve animal welfare, to drive new technologies for by-product reuse, to perform new information systems for consumers, to promote monitoring protocols and enhance competitiveness on the internal and external markets for the Piemonte dairy products, and to provide additional value which is not simply economic but also social and environmental. Livestock production chain is the target of attack due to an expensive environmental impact and some concern about animal welfare. TECH4MILK Platform arises from the need to provide a scientific, methodological, and technological response to these criticisms based on identification and dissemination of new successful solutions

The project tackles the problem with a highly innovative approach according to some specific objectives:

• development of management models designed to increase resistance to mastitis (environment management and genomic selection);
• improving the efficiency of diagnosis through the development of new approaches to the use of somatic cells, the validation of early markers of infection and the identification of pathogens and genes related to resistance;
• reduction and optimization of the use of the drug through the development of protocols for strain identification;
• determination of residues in milk;
• evaluation of the impact of treatments on the milk microbiota and microbiome.

• “TECH4MILK - Tecnologie e soluzioni innovative al servizio della filiera latte piemontese per promuoverne la competitività e la sostenibilità.” Regione Piemonte, Fondo Europeo Sviluppo Regionale - Programma Operativo Regionale “Investimenti a favore della crescita e dell’occupazione” F.E.S.R. 2014/2020 e F.S.E. 2014/2020 (bando)

• Soto del Rio M.D.L.D., Dalmasso A., Civera T., Bottero M.T. - Characterization of bacterial communities of donkey milk by high-throughput sequencing - International Journal of Food Microbiology, 251, 2017, 67-72.
• Divari S. … Sacchi P., Rasero R., Biolatti B., Cannizzo F.T. - A two-step immunomagnetic separation of somatic cell subpopulations for a gene expression profile study in bovine milk - Journal of Dairy Research, 85, 3, 2018, 281-287.
• Donalisio C. … Re G. - Effects of flunixin meglumine and ketoprofen on mediator production in ex vivo and in vitro models of inflammation in healthy dairy cows - Journal of Veterinary Pharmacology and Therapeutics, 36, 2013, 130-139.
• Liu A., Anfossi L., Shen L., Li C., Wang X. - Non-competitive immunoassay for low-molecular-weight contaminant detection in food, feed and agricultural products: A mini-review - Trends in Food Science and Technology, 71, 2018, 181-187.
• Chiesa L.M., Decastelli L. e coll. - Analysis of antibiotic residues in raw bovine milk and their impact toward food safety and on milk starter cultures in cheese-making process - LWT Food Science and Technology, 131, 2020, article number 109783.
• Macori G., Bellio A., Bianchi D.M. … Decastelli L. - Genome-wide profiling of enterotoxigenic Staphylococcus aureus strains used for the production of naturally contaminated cheeses - Genes, 11, 2020, article number 33.
• Wemette M. … Moroni P., Welcome F.L., Ivanek R. - New York State dairy farmers' perceptions of antibiotic use and resistance: A qualitative interview study - PLoS ONE, 15, 2020, article number e0232937.
• Addis M.F. … Bronzo V. - Influence of subclinical mastitis and intramammary infection by coagulase-negative staphylococci on the cow milk peptidome - Journal of Proteomics, 226, 2020, article number 103885.

• Prof. Laura Anfossi UNITO (laura.anfossi@unito.it)
• Dott. Daniela Manila Bianchi, Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta (manila.bianchi@izsto.it)
• Dott. Lucia Decastelli, Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta (lucia.decastelli@izsto.it)
• Prof. Valerio Bronzo, Università degli Studi di Milano (valerio.bronzo@unimi.it)
• Prof. Paolo Moroni, Università degli Studi di Milano (paolo.moroni@unimi.it)
• IN.AL.PI. S.p.A. (capofila del progetto)
• SOREMARTEC ITALIA S.r.l. 
• ASSOCIAZIONE REGIONALE ALLEVATORI DEL PIEMONTE